
石曜嘉
Assistant Professor
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辦公室位置:元智三館3709室
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03-4638800轉6612
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EDUCATION
- Institute of Biomedical Engineering, National Taiwan University, Taiwan - Ph.D. Sep 2010 - Jan 2019 National Taiwan
- Normal University, Taiwan - M.S. Sep 2007 - Jun 2009
- Yuan Ze University, Taiwan - B.S.
EXPERIENCE
- Graduate Institute of Medicine, Yuan Ze University, Taiwan - Assistant Professor Aug 2021 - PRESENT
- Principal Investigator at Clinical Neuroimaging and Neurocomputational Lab
- Adjunct Assistant Professor at Department of Electrical Engineering (Program A)
- Singapore General Hospital, Singapore - MR Physicist Sep 2019 - Jun 2021
- Duke-NUS Medical School, Singapore - Postdoctoral Researcher Sep 2019 - Jun 2021
- National Taiwan University Hospital, Taiwan - Postdoctoral Researcher Feb 2019 - Jun 2019
- University of Aberdeen, Scotland, UK - Honorary Research Assistant
SKILLS
- Magnetic Resonance Imaging, Neuroradiology, Neuroscience, Biomedical Engineering, Artificial Intelligence
PEER-REVIEWED JOURNAL PUBLICATIONS
- (2024). A mediating framework in resting-state connectivity between the medial prefrontal cortex and anterior cingulate in mild cognitive impairment. Aging Clinical and Experimental Research (in press).
- (2023). Quantitative iron-neuromelanin MRI associates with motor severity in Parkinson's disease and matches radiological disease classification. Frontiers in Aging Neuroscience 15:1287917. https://doi.org/10.3389/fnagi.2023.1287917
- (2023). Ultra-High-Field 7T MRI in Parkinson's Disease: Ready for Clinical Use? A Narrative Review. Quantitative Imaging in Medicine and Surgery 13(11):7607-7620. https://doi.org/10.21037/qims-23-509
- (2023). Serial deep gray nuclear DTI changes in Parkinson's disease over twelve years. Frontiers in Aging Neuroscience 15:1169254. https://doi.org/10.3389/fnagi.2023.1169254
- (2023). Microstructure of Brain Nuclei in Early Parkinson's Disease: Longitudinal Diffusion Kurtosis Imaging. Journal of Parkinson's Disease 13(2):233-242. https://doi.org/10.3233/JPD-225095
- (2022). Plasma Neurofilament Light Concentration Is Associated with Diffusion-Tensor MRI-Based Measures of Neurodegeneration in Early Parkinson's Disease. Journal of Parkinson's Disease 12(7):2135-2146. https://doi.org/10.3233/JPD-223414
- (2023). Recent advances in using diffusion tensor imaging to study white matter alterations in Parkinson's disease: A mini review. Frontiers in Aging Neuroscience 14:1018017. https://doi.org/10.3389/fnagi.2022.1018017
- (2021). Seizure Frequency Is Associated with Effective Connectivity of the Hippocampal-Diencephalic-Cingulate in Epilepsy with Unilateral Mesial Temporal Sclerosis. Brain Connectivity 11(6):457-470. https://doi.org/10.1089/brain.2020.0835
- (2021). Evaluation of trigeminal nerve tractography using two-fold-accelerated simultaneous multi-slice readout-segmented echo planar diffusion tensor imaging. European Radiology 31(2):640-649. https://doi.org/10.1007/s00330-020-07193-x
- (2020). Ultrastructural and diffusion tensor imaging studies reveal axon abnormalities in Pompe disease mice. Scientific Reports 10(1):20239. https://doi.org/10.1038/s41598-020-77193-w
- (2019). Premature white matter aging in patients with right mesial temporal lobe epilepsy: A machine learning approach based on diffusion MRI data. Neuroimage Clinical 24:102033. https://doi.org/10.1016/j.nicl.2019.102033
- (2019). White matter microstructural alterations in amblyopic adults revealed by diffusion spectrum imaging with systematic tract-based automatic analysis. British Journal of Ophthalmology 103(4):511-516. https://doi.org/10.1136/bjophthalmol-2017-311733
- (2017). Hippocampal Atrophy Is Associated with Altered Hippocampus-Posterior Cingulate Cortex Connectivity in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis. AJNR American Journal of Neuroradiology 38(3):626-632. https://doi.org/10.3174/ajnr.A5039
- (2015). Altered Cortical Thickness and Tract Integrity of the Mirror Neuron System and Associated Social Communication in Autism Spectrum Disorder. Autism Research 8(6):694-708. https://doi.org/10.1002/aur.1484
- (2015). Regional cingulum disruption, not gray matter atrophy, detects cognitive changes in amnestic mild cognitive impairment subtypes. Journal of Alzheimer's Disease 44(1):125-38. https://doi.org/10.3233/JAD-141839
- (2014). Cingulum correlates of cognitive functions in patients with mild cognitive impairment and early Alzheimer's disease: a diffusion spectrum imaging study. Brain Topography 27(3):393-402. https://doi.org/10.1007/s10548-013-0346-2
INVITED TALKS
- Advanced diffusion MRI in Parkinson's disease Academic Year Seminar at Department of Biomedical Engineering, National Yang Ming Chiao Tung University, 2021/09/30.
- Applications of MRI in neurological diseases National Taiwan University Hospital Yulin Branch International Neuroscience Symposium, 2022/03/25.
- Applications of structural and functional MRI in neurodegenerative diseases Department of Radiology, Taichung Veterans General Hospital, 2022/07/19.
- The use of structural MRI in Parkinson's disease Department of Medical Imaging, National Taiwan University Hospital, 2022/09/21.
- 擴散式磁振造影應用於高齡腦心智研究之發展現況 2023年高齡大腦心智科學X腦造影技術工作坊, 國立臺灣大學身體、心靈、文化整合影像研究中心主辦, 2023/05/05.
- 腦神經造影:結合電資工程與醫學的跨域技術 111學年度元智大學電機工程所甲組書報討論, 2023/05/17.
- 探勘新興巴金森氏症之核磁共振影像生物標記 111學年度元智大學資訊工程所書報討論, 2023/05/12.
2024
Low-intensity focused ultrasound with continuous theta burst stimulation induces human primary motor cortex functional connectivity changes
ISMRM & ISMRT Annual Meeting - Magna Cum Laude Merit Award (team)
PI
Investigating relationships between the trans-stenotic arteriovenous fistula/graft pressure gradient and the degrees of stenosis before/after percutaneous transluminal angioplasty in hemodialysis patients
YZU-FEMH grants 2023
PI
The Application of Normative MRI Data for Brain Structures in Visual System: A Case Study of Steven-Johnson Syndrome
YZU-FEMH grants 2023
Co-I
Advanced application of the low intensity focused ultrasound in neuromodulation—extended study
NHRI-112-H01. 2022-2023
PI
Using neuromelanin-sensitive and multi-shell diffusion MRI to investigate diagnostic imaging biomarkers in the brainstem nuclei for novel data-driven Parkinson's disease subtypes
NSTC-111-2222-E-155-002. 2021-2022
Co-I
Advanced application of the low intensity focused ultrasound in neuromodulation
NHRI-111-H02. 2021-2022
PI
High Angular Resolution Diffusion MRI Tractographic Atlas of Deep Axonal Projections and Its Application to Parkinson's Disease Connectometic Study
YZU-FEMH grants 2021
PI
Investigating relationships between the trans-stenotic arteriovenous fistula/graft pressure gradient and the degrees of stenosis before/after percutaneous transluminal angioplasty in hemodialysis patients
YZU-FEMH grants 2023
PI
The Application of Normative MRI Data for Brain Structures in Visual System: A Case Study of Steven-Johnson Syndrome
YZU-FEMH grants 2023
Co-I
Advanced application of the low intensity focused ultrasound in neuromodulation—extended study
NHRI-112-H01. 2022-2023
PI
Using neuromelanin-sensitive and multi-shell diffusion MRI to investigate diagnostic imaging biomarkers in the brainstem nuclei for novel data-driven Parkinson's disease subtypes
NSTC-111-2222-E-155-002. 2021-2022
Co-I
Advanced application of the low intensity focused ultrasound in neuromodulation
NHRI-111-H02. 2021-2022
PI
High Angular Resolution Diffusion MRI Tractographic Atlas of Deep Axonal Projections and Its Application to Parkinson's Disease Connectometic Study
YZU-FEMH grants 2021